Povidone K17 Pharmaceutical Excipient Injectable Grade

• Certification: ISO9001
• Grade Standard: Medicine Grade
• Type: Chemical Reagent
• State: Solid
• Volatile: Not Volatile
• Appearance: White Powder
• Model NO.: Povidone K17 Pharmaceutical excipient injectable
• Transport Package: 25kgs/Drum
• Specification: BP/USP/EP
• Trademark: DX
• Origin: China
• HS Code: 39059900
• Production Capacity: 1000mt/Year

Product Description

Product Name:Polyvinylpyrrolidone

Chemical Description:Homopolymer of 1-Vinly-2-Pyrrolidone,Polyvinylpyrrolidone

INCI/CTFA:PVP

CAS NO.:9003-39-8

 

Formula structure:

Product Properties:

Technical grade PVP(PVP K Series) products are existing as powder and water solution form,and being supplied in a wide molecular weight range,easily dissolve in water,alcohol and other organic solvents.They are highly hygroscopicity,excellent film-forming capacity,adhesiveness and chemical stability,none toxicity.

 

Specifications:

Product		Povidone K15	Povidone K17	Povidone K25	Povidone K30	Povidone K60	Povidone K90
Appearance		White or yellowish-white,hygroscopic powder or flakes
Solubility		Freely soluble in water,in ethano(96%) and in methanol,very slightly soluble in acetone.
Appearance of Solution		Clearly and not moren intensely coloured than reference solution B6,BY6 or R6
Identifications		Meet ID Tests
pH Value(5% in aqueous solution)		3.0-5.0	3.0-5.0	3.0-5.0	3.0-5.0	4.0-7.0	4.0-7.0
Viscosity(Expressed as K Value)		12.75-17.25	15.3-18.36	22.5-27.0	27.0-32.4	54.0-64.8	81.0-97.2
Adehydes(Expressed as Acetaldehyde)		500 ppm max.	500 ppm max.	500 ppm max.	500 ppm max.	500 ppm max.	500 ppm max.
Peroxides(Expressed as H2O2)		400ppm max.	400 ppm max	400 ppm max	400 ppm max	400 ppm max	400 ppm max
Formic Acid		0.5% max.	0.5% max.	0.5% max.	0.5% max.	0.5% max.	0.5% max.
Hydrazine		1ppm max.	1ppm max.	1ppm max.	1ppm max.	1ppm max.	1ppm max.
N-Vinylpyrrolidone(Impurity A)	USP27	1000 ppm max.	1000 ppm max.	1000 ppm max.	1000 ppm max.	1000 ppm max.	1000 ppm max.
	Current USP/EP/BP	10 ppm max.	10 ppm max.	10 ppm max.	10 ppm max.	10 ppm max.	10 ppm max.
2-Pyrrolidone(Impurity B)		3.0% max.	3.0% max.	3.0% max.	3.0% max.	3.0% max.	3.0% max.
Heavy Metals(as Pb)		10 ppm max.	10 ppm max.	10 ppm max.	10 ppm max.	10 ppm max.	10 ppm max.
Water		5.0% max.	5.0% max.	5.0% max.	5.0% max.	5.0% max.	5.0% max.
Sulphated Ash		0.1% max.	0.1% max.	0.1% max.	0.1% max.	0.1% max.	0.1% max.
Nitrogen Content		11.5-12.8%	11.5-12.8%	11.5-12.8%	11.5-12.8%	11.5-12.8%	11.5-12.8%

 

Applications:

Povidone is one of the most important excipient in the worldwide for pharmaceutical industry,

whatever for human health care products and animal health care products.It's more and more

used as:

1)Binder for tables,capsule,

2)Sugar coatings and films,

3)Thickening agent,

4)Solubility Improver for poorly soluble drugs,

5)Bioavailability Enhancer for drug's active ingredients,

6)Pore-forming for membrane products.

example:PVP K30 used as adhesive in medicine products,PVP-K17 for Injection purpose